Publications (after 2019)


S. Nishimura, T. Yoshida, N. Higashi, T. Koga

Regulation of Cell Adhesion on Physically Crosslinked Hydrogels Composed of Amino Acid-based Polymers by Changing Elastic Modulus using Shape Fix/Memory Properties

Advanced Materials Technologies, 2024, 2301598.  DOI:10.1002/admt.202301598
M. Nakamura, S. Nishimura, N. Higashi, T. Koga

Thermo-responsive Injectable Hydrogels from Linear and Star-Shaped Block Copolymers Composed of Amino Acid-derived Vinyl Polymer and Poly(ethylene glycol) for Biomedical Applications

Materials Advances, 2024, 5, 665-674.  DOI:10.1039/D3MA00954H


D. Miyake, J. He, F. Asai, M. Hara, T. Seki, S. Nishimura, M. Tanaka, Y. Takeoka

Optically Transparent and Color-stable Elastomer with Structural Coloration under Elongation

Langmuir, 2023, 39, 17844-17852.  DOI:10.1021/acs.langmuir.3c02442
S. Nishimura, D. Sato, T. Koga

Mechanically Tunable Hydrogels with Self-healing and Shape Memory Capabilities from Thermo-responsive Amino Acid-derived Vinyl Polymers

Gels, 2023, 9, 829.  DOI:10.3390/gels9100829
S. Nishimura, M. Tanaka

The Intermediate Water Concept for Pioneering Polymeric Biomaterials: A Review and Update

Bulletin of the Chemical Society of Japan, 2023, 96, 1052-1070. (Inside Cover in this issue)  DOI:10.1246/bcsj.20230168
A. Sawamoto, S. Nishimura, N. Higashi, T. Koga

Synthesis of Amino Acid-derived Vinyl Polymers with Precisely Controlled Hydropathy and Their Thermoresponsive Behavior in Water

Polymer Chemistry, 2023, 14, 2857-2864. (Front Cover in this issue)  DOI:10.1039/D3PY00353A
S. Nishimura

環境に調和するプラスチックの開発基盤 ~ケミカルリサイクル性と材料特性を両立する合成戦略~

化学, 78, 61-62 (2023).
S. Nishimura, M. Tanaka,

生体親和性を有するテーラーメイド型温度応答性ポリ(N-(ω-アクリロイロキシアルキル)-2-ピロリドン) の設計と合成,

Journal of Japanese Society for Biomaterials, 2023, 41, 24-25.
T. Koga,


Journal of the Japan Society of Colour Material, 2023, 96, 53-57.  DOI:10.4011/shikizai.96.53


T. Koga, Y. Oatari, H. Motoda, S. Nishimura, Y. Sasaki, Y. Okamoto, D. Yamamoto, A. Shioi, N. Higashi,

Star-shaped Peptide-polymer Hybrids as Fast pH-responsive Supramolecular Hydrogels,

Biomacromolecules, 2022, 23, 2941-2950.  DOI:10.1021/acs.biomac.2c00411
S. Shiomoto, K. Inoue, H. Higuchi, S. Nishimura, H. Takaba, M. Tanaka, M. Kobayashi,

Characterization of Hydration Water Bound to Choline Phosphate-Containing Polymers,

Biomacromolecules, 2022, 23, 2999-3008.  DOI:10.1021/acs.biomac.2c00484
Y. Ikemoto, Y. Harada, M. Tanaka, S. Nishimura, D. Murakami, Y. Kurahashi, T. Moriwaki, K. Yamazoe, H. Washizu, Y. Ishii, H. Torii,

Infrared Spectra and Hydrogen-Bond Configurations of Water Molecules at the Interface of Water-Insoluble Polymers under Humidified Conditions,

The Journal of Physical Chemistry B, 2022, 126, 4143-4151.  DOI:10.1021/acs.jpcb.2c01702
古賀 智之・東 信行

アミノ酸系高分子で機能化したナノ粒子の創製、高分子微粒子の最新技術動向 (シーエムシー出版) 第1編, 第6章,

48-57 (2022).
T. Koga, A. Ikejiri, N. Higashi,

Narcissistic Self-sorting of Amphiphilic Collagen-inspired Peptides in Supramolecular Vesicular Assemblies,

Langmuir, 2022, 38, 2294-2300.  DOI:10.1021/acs.langmuir.1c02978
S. Nishimura, K. Nishida, S. Shiomoto, M. Tanaka,

Surfactant-Free Suspension Polymerization of Hydrophilic Monomers with an Oil-in-Water System for the Preparation of Microparticles Toward the Selective Isolation of Tumor Cells,

Materials Advances, 2022, 3, 5043-5054.  DOI:10.1039/D2MA00129B
S. Nishimura, K. Nishida, T. Ueda, S. Shiomoto, M. Tanaka,

Poly(N-(ω-acryloyloxy-n-alkyl)-2-pyrrolidone)s with Widely-tunable Lower Critical Solution Temperatures (LCSTs): A Promising Alternative to Poly(N-isopropylacrylamide),

Polymer Chemistry, 2022. 13, 2519-2530.  DOI:10.1039/D2PY00154C


T. Koga, T. Morishita, Y. Harumoto, S. Nishimura, N. Higashi,

Spider Silk-inspired Peptide Multiblock Hybrid Copolymers for Self-healable Thin Film Materials,

Materials Advances, 2021, 2, 7851-7860. (Front cover in this issue.)  DOI:10.1039/D1MA00823D
東 信行・猿田 孟徳・古賀 智之


同志社大学ハリス理化学研究報告, 2021, 62, 55-62.  DOI:10.14988/00028386
T. Koga, T. Matsuoka, Y. Morita, N. Higashi,

Injectable Hydrogels Self-assembled from Oligopeptide-Poly(2-methacryloyloxyethyl phosphorylcholine) Hybrid Graft Copolymers for Cell Scaffolds and Controlled Release Applications,

Materials Advances, 2021, 2, 4068-4074.  DOI:10.1039/D1MA00347J

T. Koga, S. Kingetsu, N. Higashi,

Supramolecular Nanofibers from Collagen-mimetic Peptides Bearing Various Aromatic Groups at N-Termini via Hierarchical Self-assembly,

International Journal of Molecular Sciences, 2021, 22, 4533 (1-11).  DOI:10.3390/ijms22094533


古賀 智之・西村 慎之介・東 信行


ファインケミカル, 49(8), 12-17 (2020).
T. Yamano, N. Higashi, T. Koga,

Unique Self-assembly of Sequence-controlled Amino Acid Derived Vinyl Polymer with Gradient Thermoresponsiveness along a Chain,

Langmuir, 2020, 36, 6550-6556.  DOI:10.1021/acs.langmuir.0c01036
N. Higashi, R. Yoshikawa, T. Koga,

Photo-responsive Azobenzene Interactions Promote Hierarchical Self-assembly of Collagen Triple-Helical Peptides to Various Higher-order Structures,

RSC Advances, 2020, 10, 15947-15954.  DOI:10.1039/D0RA02906H
古賀 智之・東 信行


「自己修復材料・自己組織化・形状記憶材料の開発と応用事例」(技術情報協会), 第6章, 第8節, 424-429 (2020).
T. Koga, K. Tomimori, N. Higashi,

Transparent, High Strength, and Shape-memory Hydrogels from Thermo-responsive Amino Acid-derived Vinyl Polymer Networks,

Macromolecular Rapid Communications, 2020, 41, 1900650 (1-7).  DOI:10.1002/marc.201900650
T. Yamano, N. Higashi, T. Koga,

Precisely Synthesized Sequence-controlled Amino Acid-derived Vinyl Polymers: New Insights into Thermo-responsive Polymer Design,

Macromolecular Rapid Communications, 2020, 41, 1900550 (1-8).  DOI:10.1002/marc.201900550


S. Nishimura, N. Hokazono, Y. Taki, H. Motoda, Y. Morita, K. Yamamoto, N. Higashi, T. Koga,

Photocleavable Peptide-Poly(2-hydroxyethyl methacrylate) Hybrid Graft Copolymer via Post-polymerization Modification by Click Chemistry to Modulate the Cell Affinities of 2D and 3D-Materials,

ACS Applied Materials Interfaces,2019, 11, 24577-24587.  DOI:10.1021/acsami.9b06807
N. Higashi, K. Narimatsu, M. Okumura, S. Nishimura, T. Koga,

Spontaneous Formation of Nanoparticles from Peptide-Vinyl Polymer Diblock Hybrids Prepared by RAFT Polymerization and Their Interactions with Cells,

ACS Omega, 2019, 4, 8104-8111.  DOI:10.1021/acsomega.9b00899
西村 慎之介・東 信行・古賀 智之

アミノ酸からつくる機能性ポリマーによる生体適合性表面の設計, 「無機/有機材料の表面 処理・改質による生体適合性付与」

(シーエムシー出版),第4章, 173-181 (2019).
S. Nishimura, N. Higashi, T. Koga,

A Novel Thermo-responsive Multiblock Architecture Composed
of a Sequential Peptide and an Amino Acid-derived Vinyl Polymer: Toward Protein-mimicking
Single-chain Folding,

Chemical Communications, 2019, 55, 1498-1501.  DOI:10.1039/C8CC09051C
S. Nishimura, N. Higashi, T. Koga,

Synthesis of Peptide–Vinyl Polymer Multiblock Hybrids by Nitroxide-mediated Polymerization: Breaking the Limitations of Monomer Compatibility,

Polymer Chemistry, 2019, 10, 71-76. (Cover picture in this issue)  DOI:10.1039/C8PY01330F